Application & Markets

Life Science/Biology

Life Science is a very broad scientific term referring to the study of living organisms. A few related sub-fields include biology, biochemistry, biophysics, and medicine. Life science applications aim at understanding how cell function and their place in the ecosystem.

Life Science/Biology

Life Science

The applications of photons in medicine and healthcare, to improve the quality of life, is quickly growing.. Benefits include lower cost prescriptions, the reduced drug abuse,
minimally invasive and non-invasive treatments, pain relief, and faster recovery all are only a few. Cancer, immuno-chemistry, pharmacology and neurology are a few medical research areas benefiting from high-resolution imaging using laser scanning microscopy techniques.

Some of the most common light modalities for biological imaging are:

  • Single photon – Fluorescent Lifetime Imaging (FLIM), Foerster Resonance Energy Transfer (FRET), Pulsed Interleaved Excitation (PIE), Fluorescence Correlation Spectroscopy (FCS), Single Molecule Detection (SMD), etc.
  • Multi-photon – two-photon (2p), three-photon (3p), Second-Harmonic Generation (SHG), Coherent Anti-Stokes Scattering (CARS), Stimulated Raman Scattering (SRS), and other nonlinear techniques.
LIGHT SHEET Z-stack of unlabeled honey-bee (0.63x, 0.15 NA, FOV 21 x 21 mm) - excitation at 488 nm (blue); clearing: BABB over 2 weeks.
LABEL-FREE 3D TISSUE IMAGING - Mouse colon – unstained (16x, FOV 570 µm) – z-stack 230 µm

Products

Multi-photon Microscope

Our lasers are designed to integrate into any multi-photon imaging system. Multiple outputs, ultrashort pulses <130 fs and tunable between 750 nm to 1300 nm with up to 8W 45 output power. Perfectly matched for 2P/SHG/THG-imaging, but also 3-photon, CARS, SRS and other nonlinear techniques. We will customize them for your specific needs.

Femtosecond Sources

Our lasers are designed to integrate into any multi-photon imaging system. Multiple outputs, ultrashort pulses <130 fs and tunable between 750 nm to 1300 nm with up to 8W 45 output power. Perfectly matched for 2P/SHG/THG-imaging, but also 3-photon, CARS, SRS and other nonlinear techniques. We will customize them for your specific needs.

Picosecond Pulsed

The picosecond pulsed sources are either diode- or LED-based devices that can be operated at variable, user-adjustable repetition rates up to 200 MHz. They cover discrete wavelengths from 255 nm to 1990 nm.

High-power and UV Lasers

The VisUV/VisIR lasers based on a Master Oscillator Fiber Amplifier (MOFA) concept with optional frequency conversion. The stand-alone units emit picosecond pulses at repetition rates up to 80 MHz. Infrared versions with average powers up to 1.5W (VisIR) as well as units that emit in the ultraviolet at 266, 280 or 295 nm (VisUV) are available.

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